Discussion: Chromosomal DNA Movement
Discussion: Chromosomal DNA Movement
Discussion: Chromosomal DNA Movement
Discussion: Chromosomal DNA Movement.
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- What major event occurs during interphase?
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- A person, residing in a location where they are exposed to the sun often, develops a mutation in some of their skin cells resulting in cancer. Consider whether their offspring will be born with the same mutation. Use scientific evidence to support your answer.
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Experiment 1: Following Chromosomal DNA Movement through Meiosis
Data Tables and Post-Lab Assessment
Part 1 – Meiotic Division Beads Diagram without Crossing Over
Prophase I
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>metaphase
Metaphase I
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>anaphase
Anaphase I
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>telophase
Telophase I
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Prophase II
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>metaphase ii
Metaphase II
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Anaphase II
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>telophase ii
>telophase ii
Telophase II
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Cytokinesis
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meiotic division beads diagram
Part 2: Meiotic Division Beads Diagram with Crossing Over
Prophase I
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>metaphase
Metaphase I
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>anaphase
Anaphase I
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>telophase
Telophase I
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Prophase II
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>metaphase ii
Metaphase II
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Anaphase II
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>telophase ii
>telophase ii
Telophase II
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Cytokinesis
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Post-Lab Questions
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1. What is the ploidy of the DNA at the end of meiosis I? What about at the end of meiosis II?
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2. How are meiosis I and meiosis II different?
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3. Why do you use non-sister chromatids to demonstrate crossing over?
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4. What combinations of alleles could result from a crossover between BD and bd chromosomes?
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5. How many chromosomes were present when meiosis I started?
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6. How many nuclei are present at the end of meiosis II? How many chromosomes are in each?
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7. Identify two ways that meiosis contributes to genetic recombination.
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8. Why is it necessary to reduce the number of chromosomes in gametes, but not in other cells?
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9. Blue whales have 44 chromosomes in every cell. Determine how many chromosomes you would expect to find in the following:
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Sperm Cell:
Egg Cell:
Daughter Cell from Meiosis I:
Daughter Cell from Meiosis II:
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10.Research and find a disease that is caused by chromosomal mutations. When does the mutation occur? What chromosomes are affected? What are the consequences?
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11.Diagram what would happen if sexual reproduction took place for four generations using diploid (2n) cells.
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Experiment 2: The Importance of Cell Cycle Control
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Data
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Post-Lab Questions
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1. Record your hypothesis from Step 1 in the Procedure section here.
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2. What do your results indicate about cell cycle control?
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3. Suppose a person developed a mutation in a somatic cell which diminishes the performance of the body’s natural cell cycle control proteins. This mutation resulted in cancer, but was effectively treated with a cocktail of cancer-fighting techniques. Is it possible for this person’s future children to inherit this cancer-causing mutation? Be specific when you explain why or why not.
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4. Why do cells which lack cell cycle control exhibit karyotypes which look physically different than cells with normal cell cycle.
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5. What are HeLa cells? Why are HeLa cells appropriate for this experiment?
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